Gold(III) Complexes for Antitumor Applications: An Overview.
Clicks: 235
ID: 95439
2018
Article Quality & Performance Metrics
Overall Quality
Improving Quality
0.0
/100
Combines engagement data with AI-assessed academic quality
Reader Engagement
Steady Performance
30.0
/100
234 views
29 readers
Trending
AI Quality Assessment
Not analyzed
Abstract
Gold(III) complexes have emerged as a versatile and effective class of metal-based anticancer agents. The development of various types of ligands capable of stabilizing the Au cation and preventing its reduction under physiological conditions, such as chelating nitrogen-donors, dithiocarbamates and C^N cyclometalled ligands, has opened the way for the exploration of their potential intracellular targets and action mechanisms. At the same time, the bioconjugation of Au complexes has emerged as a promising strategy for improving the selectivity of this class of compounds for cancer cells over healthy tissues, and recent developments have shown that combining gold complexes with molecular structures that are specifically recognized by the cell can exploit the cell's own transport mechanisms to improve selective metal uptake.
Abstract Quality Issue:
This abstract appears to be incomplete or contains metadata (121 words).
Try re-searching for a better abstract.
| Reference Key |
bertrand2018goldiiichemistry
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Bertrand, Benoît;Williams, Morwen R M;Bochmann, Manfred; |
| Journal | Chemistry (Weinheim an der Bergstrasse, Germany) |
| Year | 2018 |
| DOI |
10.1002/chem.201800981
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.