Glycation and Antioxidants: Hand in glove of antiglycation and natural antioxidants.

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ID: 94794
2020
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Abstract
The non-enzymatic interaction of sugar and protein resulting in the formation of advanced glycation end products responsible for cell signaling alterations ultimately lead to the human chronic disorders such as diabetes mellitus, cardiovascular diseases, cancer, etc. Studies suggest that AGEs upon interaction with receptors for advanced glycation end products (RAGE) result in the production of pro-inflammatory molecules and free radicals that exert altered gene expression effect. Till date many studies unveiled the potent role of synthetic and natural agents in inhibiting the glycation reaction at lesser or greater extent. This review focuses on the hazards of glycation reaction and its inhibition by natural antioxidants including polyphenols.
Reference Key
khanam2020glycationcurrent Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Khanam, Afreen;Ahmad, Saheem;Husain, Arbab;Rehman, Shahnawaz;Farooqui, Alvina;Yusuf, Mohd Aslam;
Journal current protein & peptide science
Year 2020
DOI
10.2174/1389203721666200210103304
URL
Keywords
polyphenols diabetic complications glycation antiglycation advanced glycation end-products

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