Selective Binding of Dopamine and Epinephrine in Water by Molecularly Imprinted Fluorescent Receptors.

Clicks: 179
ID: 94779
2020
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Abstract
Catecholamines play important roles in biology but their structural similarity makes it challenging to construct synthetic receptors with selective binding. A combination of covalent and noncovalent binding groups in the hydrophobic core of water-soluble nanoparticles enabled them to recognize dopamine and epinephrine with an association constant (Ka) of 3-4 × 104 M -1 in water, an order of magnitude higher than previously reported. In addition, minute structural changes among analogues were detected including the addition or removal of a single hydroxyl or methyl group.
Reference Key
duan2020selectivechemistry Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Duan, Likun;Zhao, Yan;
Journal Chemistry, an Asian journal
Year 2020
DOI
10.1002/asia.201901783
URL
Keywords
molecular recognition binding molecular imprinting host micelle

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