Induces , and Gene Expression as Part of the Inflammatory Response in RAW264.7 Cells.

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ID: 94686
2009
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Abstract
Genes related to -induced inflammation were identified using the gene-fishing technology, an improved method for identifying differentially expressed genes (DEGs) using an annealing control primer (ACP) system in RAW264.7 cells. After treatment with , 16 DEGs were expressed in RAW264.7 cells using a pre-screening system. Among these 16 DEGs, 11 DEGs (DEGs 1, 4, 5-10, 12-15) were selected and sequenced directly, revealing that DEG12 (Grap), DEG14 (Gadd45), and DEG15 () were related to inflammatory cytokines. This is the first report that intact induces the expression of in RAW264.7 cells. Subsequently, these genes may be targets for screening novel inhibitors of the mycoplasmal inflammatory response.
Reference Key
hwang2009toxicological Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Hwang, Mi-Hyun;Choi, Myung-Jin;Park, Seung-Chun;
Journal toxicological research
Year 2009
DOI
10.5487/TR.2009.25.3.119
URL
Keywords
genefishing mycoplasma hyopneumoniae mycoplasmal inflammatory response raw264.7 cells

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