Cell-phone-based platform for biomedical device development and education applications.
Clicks: 165
ID: 93827
2011
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Abstract
In this paper we report the development of two attachments to a commercial cell phone that transform the phone's integrated lens and image sensor into a 350x microscope and visible-light spectrometer. The microscope is capable of transmission and polarized microscopy modes and is shown to have 1.5 micron resolution and a usable field-of-view of 150 x 50 with no image processing, and approximately 350 x 350 when post-processing is applied. The spectrometer has a 300 nm bandwidth with a limiting spectral resolution of close to 5 nm. We show applications of the devices to medically relevant problems. In the case of the microscope, we image both stained and unstained blood-smears showing the ability to acquire images of similar quality to commercial microscope platforms, thus allowing diagnosis of clinical pathologies. With the spectrometer we demonstrate acquisition of a white-light transmission spectrum through diffuse tissue as well as the acquisition of a fluorescence spectrum. We also envision the devices to have immediate relevance in the educational field.
| Reference Key |
smith2011cellphonebasedplos
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| Authors | Smith, Zachary J;Chu, Kaiqin;Espenson, Alyssa R;Rahimzadeh, Mehdi;Gryshuk, Amy;Molinaro, Marco;Dwyre, Denis M;Lane, Stephen;Matthews, Dennis;Wachsmann-Hogiu, Sebastian; |
| Journal | PloS one |
| Year | 2011 |
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