Antifungal, anti-inflammatory and antioxidant activity of bi-herbal phytotherapic using medicinal plants from Argentina highlands.

Clicks: 587
ID: 93146
2020
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #7 of 1,183 articles by views in Journal of ethnopharmacology

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 1,183 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The Argentinean medicinal plants Larrea divaricata Cav., Larrea cuneifolia Cav., Larrea nitida Cav., Zuccagnia punctata Cav. and Tetraglochin andina Ciald are used alone and in combined in traditional medicine by inhabitants from Argentinean northwestern to solve mycosis, vaginal infections, gastrointestinal, respiratory, and inflammatory process.To assess the effect of interactions between dry extracts of these five species of medicinal plants against yeast strains isolated from vaginal infections, select the most active mixtures and evaluate the anti-inflammatory and antioxidant activities.Synergy between the plants extracts was studied using a broth microdilution assay by the checkerboard method against Saccharomyces cerevisiae, Candida albicans, and non albicans strains. The inhibitory effect on lipoxygenase enzyme and the antioxidant capacity in cell free and cell systems were studied. The chemical profile was evaluated by qualitative and quantitative screening, whereas chemical markers were quantified by HPLC-DAD.A synergistic antifungal effect was observed in some of the binary combinations. Z. punctata/L. divaricata, Z. punctata/L. cuneifolia, and Z. punctata/L. nitida were the most active mixtures. Nordihydroguaiaretic acid and 2',4'-dihydroxychalcone, two antifungal compounds present in these extracts, were identified and quantified by HPLC-DAD. Both the single extracts and the bi-herbal mixtures showed antioxidant activity (in cellular and in cell-free systems) and were active on pro-inflammatory enzymes (LOX).Our results indicated that the most active combinations of these species extracts could be useful in the treatment of vaginal infectious diseases caused by Saccharomyces cerevisiae and Candida spp. strains and in the associated oxidative and inflammatory processes. In addition, the results highlighted the potential phyto-therapeutic of total phytochemical compounds present in these medicinal plants.
Reference Key
moreno2020antifungaljournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Moreno, María Alejandra;Zampini, Iris Catiana;Isla, María Inés;
Journal Journal of ethnopharmacology
Year 2020
DOI
S0378-8741(19)34245-X
URL
Keywords
antioxidant synergism anti-inflammatory antifungal argentinean medicinal plant extracts

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.