Chemotherapy in the definitive management of oral cancers: Where do we stand today?

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ID: 93006
2020
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Abstract
The treatment of locally advanced oral cavity cancer is often multimodal, involving surgical resection, radiotherapy (RT), and chemotherapy. Systemic therapy is the mainstay of treatment for recurrent/metastatic disease. While the concurrent use of cisplatin with post-operative RT is well established in patients with high risk features of extranodal extension and/or positive surgical margins following resection, the role of chemotherapy in other curative settings is not clear. Studies reporting success of induction chemotherapy or definitive chemoradiotherapy in absence of primary resection include all anatomic sites of head and neck cancer, and oral cavity cancer subset is rarely reported as a separate analysis, thus limiting the interpretation of results. This article will focus on the use of systemic therapy for locoregionally advanced oral cavity cancer.
Reference Key
geiger2020chemotherapyoral Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Geiger, Jessica L;Adelstein, David J;
Journal oral oncology
Year 2020
DOI
S1368-8375(20)30020-8
URL
Keywords
Chemotherapy head and neck cancer squamous cell carcinoma adjuvant therapy cisplatin systemic therapy oral cavity cancer

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