Immunosensor Based on Long-Period Fiber Gratings for Detection of Viruses Causing Gastroenteritis.
Clicks: 270
ID: 92837
2020
Article Quality & Performance Metrics
Overall Quality
Improving Quality
0.0
/100
Combines engagement data with AI-assessed academic quality
Reader Engagement
Steady Performance
64.7
/100
263 views
207 readers
Trending
AI Quality Assessment
Not analyzed
Abstract
Since the norovirus is the main cause of acute gastroenteritis all over the world, its fast detection is crucial in medical diagnostics. In this work, a rapid, sensitive, and selective optical fiber biosensor for the detection of norovirus virus-like particles (VLPs) is reported. The sensor is based on highly sensitive long-period fiber gratings (LPFGs) coated with antibodies against the main coat protein of the norovirus. Several modification methods were verified to obtain reliable immobilization of protein receptors on the LPFG surface. We were able to detect 1 ng/mL norovirus VLPs in a 40-min assay in a label-free manner. Thanks to the application of an optical fiber as the sensor, there is a possibility to increase the user's safety by separating the measurement point from the signal processing setup. Moreover, our sensor is small and light, and the proposed assay is straightforward. The designed LPFG-based biosensor could be applied in both fast norovirus detection and in vaccine testing.
| Reference Key |
janczukrichter2020immunosensorsensors
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Janczuk-Richter, Marta;Gromadzka, Beata;Richter, Łukasz;Panasiuk, Mirosława;Zimmer, Karolina;Mikulic, Predrag;Bock, Wojtek J;Maćkowski, Sebastian;Śmietana, Mateusz;Niedziółka Jönsson, Joanna; |
| Journal | sensors |
| Year | 2020 |
| DOI |
E813
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.