Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
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ID: 90183
2012
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Abstract
A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, <strong>1</strong>) together with the known alkaloid stigmalactam (<strong>2</strong>), were isolated from <em>Orophea enterocarpa</em>. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds <strong>1</strong> and <strong>2</strong> exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC<sub>50</sub> values of 1.68 and 1.32 μM, respectively.
| Reference Key |
nayyatip2012aristolactamtypeinternational
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|---|---|
| Authors | Nayyatip, S. |
| Journal | International journal of molecular sciences |
| Year | 2012 |
| DOI |
10.3390/ijms13045010
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| URL | |
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