[Relationship between exposure to air pollutants during pre-pregnancy or early pregnancy and birth defects in Xi'an, 2013-2015: a case crossover study].

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2017
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Abstract
To understand the levels of exposure to traffic-related air pollutants including nitrogen dioxide (NO(2)), PM(10) and PM(2.5), and the relationship between the exposure to air pollutants during pre-pregnancy or early pregnancy and birth defects. Data on air pollution and birth defects from 2013 to 2015 was collected. A case-crossover design was employed to analyze the exposure-response relationship between traffic-related air pollutants and birth defects. A total of 4 235 pregnant women were studied. During the study period, the daily average concentrations of ambient NO(2), PM(10) and PM(2.5) appeared as 60.83 μg/m(3), 104.94 μg/m(3) and 103.88 μg/m(3), respectively, with the concentration of PM(2.5) larger than the 2(nd) version of Standard National Ambient Air Quality Standard. In addition, there were strong correlations seen between each of the pollutants (<0.01). After adjustment for the influence of meteorological factors, it was found that the exposure to high level of NO(2) and PM(10) during pre-pregnancy or early pregnancy increased the risk on birth defects (<0.05). Levels of exposure to adverse environmental factors during pre- pregnancy or early pregnancy could increase the risk of birth defects, suggesting that in these sensitive periods, women should try to avoid being exposed to high concentration of traffic-related air pollutants as NO(2), PM(10) . in order to reduce the risk of birth defects.
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zhang2017relationshipzhonghua Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Q Zhang, X M Xiang, H Song, M Dong, S P Zhang, B B Mi, L L Wang, L Zhang, H Yan, S N Dang
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Journal zhonghua liu xing bing xue za zhi = zhonghua liuxingbingxue zazhi
Year 2017
DOI
10.3760/cma.j.issn.0254-6450.2017.12.019
URL
Keywords
air pollutants birth defects case-crossover study

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