Bactericidal efficacy of cold atmospheric plasma treatment against multidrug-resistant .

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ID: 89860
2020
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Abstract
The global of spread multidrug-resistant has become a public health threat. Cold atmospheric plasma (CAP) is reported to have bactericidal efficacy; however, its effects on clinical super multidrug-resistant are unclear. The aim of this study was to investigate the bactericidal efficacy of CAP on a strain of super multidrug-resistant . The effects of CAP treatments were evaluated using assays for the detection of growth, viability, metabolism, virulence factors and reactive oxygen species (ROS) levels. Both CAP treatments dose-dependently inhibited cell viability and metabolic activity, and decreased the expression of several virulence factors. CAP treatment induced a significant increase in intracellular ROS levels, and ROS scavengers inhibited this effect. CAP treatment is a promising option for the clinical inhibition of multidrug-resistant , and the development of CAP technologies might be the key to solving the long-standing problem of drug-resistant bacteria.
Reference Key
wang2020bactericidalfuture Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Wang, Liyun;Xia, Chuankai;Guo, Yajun;Yang, Chunjun;Cheng, Cheng;Zhao, Jun;Yang, Xingyu;Cao, Zhicheng;
Journal future microbiology
Year 2020
DOI
10.2217/fmb-2019-0265
URL
Keywords
reactive oxygen species cap cap treatments cap-activated liquid cold atmospheric plasma multidrug-resistant pseudomonas aeruginosa

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