Single-shot K-Edge subtraction X-ray discrete computed tomography with a polychromatic source and the Pixie-III detector.

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ID: 87582
2020
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Abstract
K-Edge Subtraction (KES) imaging is a technique able to map a specific element such as e.g. a contrast agent within the tissues, by exploiting the sharp rise of its absorption coefficient at the K-Edge energy. Whereas mainly explored at synchrotron radiation sources, the energy discrimination properties of modern X-ray Photon Counting Detectors (XPCDs) pave the way for an implementation of single-shot KES imaging with conventional polychromatic sources. In this work we present an X-ray CT imaging system based on the innovative Pixie-III detector and discrete reconstruction. The results reported here show that a reliable automatic localization of Barium (above a certain concentration) is possible with a few dozens of tomographic projections for a volume having an axial slice of 512×512 pixels. The final application is a routine high-fidelity 3D mapping of a specific element ready for further morphological quantification by means of X-ray CT with potential promising applications in vivo.
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brun2020singleshotphysics Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Brun, Francesco;Di Trapani, Vittorio;Albers, Jonas;Sacco, Pasquale;Dreossi, Diego;Brombal, Luca;Rigon, Luigi;Longo, Renata;Mittone, Alberto;Dullin, Christian;Bravin, Alberto;Delogu, Pasquale;
Journal Physics in medicine and biology
Year 2020
DOI
10.1088/1361-6560/ab7105
URL
Keywords
contrast agent computed tomography discrete reconstruction photon counting detector spectral imaging

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