Iron oxide nanoparticles for magnetically-guided and magnetically-responsive drug delivery
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ID: 86261
2015
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Abstract
In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.
| Reference Key |
estelrich2015ironinternational
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|---|---|
| Authors | Estelrich, J. |
| Journal | International journal of molecular sciences |
| Year | 2015 |
| DOI |
10.3390/ijms16048070
|
| URL | |
| Keywords | Keywords not found |
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