A role for ABIL3 in plant cell morphogenesis.

Clicks: 154
ID: 86046
2010
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #24 of 29 articles by views in The Plant journal : for cell and molecular biology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Actin nucleation facilitated by the ARP2/3 complex plays a central role in plant cell shape development. The molecular characterization of the distorted class of trichome mutants has recently revealed the SCAR/WAVE complex as an essential upstream activator of ARP2/3 function in plants. The SCAR/WAVE complex is conserved from animals to plants and, generally, is composed of the five subunits SCAR/WAVE, PIR121, NAP125, BRICK and ABI. In plants, four of the five subunits have been shown to participate in trichome and pavement morphogenesis. Plant ABI-like proteins (ABIL), however, which constitute a small four-member protein family in Arabidopsis thaliana, have not been characterized functionally, so far. Here we demonstrate that microRNA knock-down of the ABIL3 gene leads to a distorted trichome phenotype reminiscent of ARP2/3 mutant phenotypes and consistent with a crucial role of the ABIL3 protein in an ARP2/3-activating SCAR/WAVE complex. In contrast to ARP2/3 mutants, however, the ABIL3 knock-down stimulated cell elongation in the root, indicating distinct functions of the ABIL3 protein in different tissues. Furthermore, we provide evidence that ABIL3 associates with microtubules in vivo, opening up the intriguing possibility that ABI-like proteins have a function in linking SCAR/WAVE-dependent actin nucleation with organization of the microtubule cytoskeleton.
Reference Key
jorgens2010athe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jörgens, Cordula I;Grünewald, Nora;Hülskamp, Martin;Uhrig, Joachim F;
Journal The Plant journal : for cell and molecular biology
Year 2010
DOI
10.1111/j.1365-313X.2010.04210.x
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.