The tetrazole 3-N-oxide synthesis.

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ID: 83182
2010
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Abstract
An efficient procedure for transferring an oxygen atom to the 1- or 2-substituted 5-alkyl or aryl tetrazole ring, resulting, for the first time, in the corresponding N-oxides, was developed using HOF.CH(3)CN. This novel route features mild conditions and high yields. X-ray structure analysis and (15)N NMR experiments indicate that the preferred position for the incorporation of the oxygen is on the N-3 atom.
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harel2010thethe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Harel, Tal;Rozen, Shlomo;
Journal The Journal of organic chemistry
Year 2010
DOI
10.1021/jo100278z
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