Antinociceptive effects of aqeous extract Launaea acanthodes gum in mice

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ID: 81049
2017
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Abstract
Introduction: Previous studies indicated that Launaea acanthodes (LA) can be effective against epilepsy, nervous disorder, local and articular pain and convulsion disorders. The aim of this study was to assessment the antinoceceptive effects of  LA on peripheral and visceral pain in mice by using hot plate (HP), tail flick (TF), formalin (FT) and writhing (WR) tests. Materials and Methods: In this study 160 young adult male albino mice (25-30 g) were used (n = 8 in each group). Aqueous extract of LA gum (50, 100, and 200 mg/Kg IP) and saline (SAL) were injected 30 min before the pain evaluation tests. Acute and chronic pain was assessed by HP, TF and FT models and visceral pain was assessed by writhing test. Results: Results indicated that LA has analgesic effects (P< 0.05) in comparison with the control and saline groups  and higher dose of LA was more effective (P< 0.001). Conclusion: The above findings showed that LA have modulatory effects on acute, chronic and visceral pain
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nazari2017antinociceptivemajallahi Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Nazari, Hossein;Bidokhty, Shayan ;Mohammadi, Abolfazl;Jafari, Maryam;Taherian, Abbas Ali ;
Journal majallah-i ̒ilmī-i dānishgāh-i ̒ulūm-i pizishkī-i simnān
Year 2017
DOI
DOI not found
URL
http://koomeshjournal.semums.ac.ir/browse.php?a_code=A-10-10-3&slc_lang=en&sid=1
Keywords
Infectious and parasitic diseases Veterinary medicine Medicine (General) Medicine surgery food processing and manufacture geography (general) nutrition. foods and food supply diseases of the endocrine glands. clinical endocrinology

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