Antimicrobial Secondary Metabolites from the Seawater-Derived Fungus SW9.

Clicks: 400
ID: 80565
2019
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #79 of 729 articles by views in molecules

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 729 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Marine-derived fungi are considered to be valuable producers of bioactive secondary metabolites used as lead compounds with medicinal importance. In this study, chemical investigation of the seawater-derived fungus SW9 led to the isolation and identification of one new quinazolinone alkaloid, 2-(4-hydroxybenzyl)-4-(3-acetyl)quinazolin-one (), one new aromatic bisabolene-type sesquiterpenoid, () and one new chorismic acid analogue (), as well as two known alkaloids (compounds and ). Their structures were determined by extensive 1D/2D NMR and mass spectrometric data, and the absolute configurations of and were assigned by the analysis of ECD spectra aided by quantum chemical computations. Compounds , and exhibited selective inhibitory activities against the human pathogenic bacteria , , and , with MIC values ranging from 2.0 to 16 μg/mL.
Reference Key
liu2019antimicrobialmolecules Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Liu, Yu-Jing;Zhang, Jian-Long;Li, Chen;Mu, Xue-Gen;Liu, Xiao-Li;Wang, Lei;Zhao, Yan-Cui;Zhang, Peng;Li, Xiao-Dong;Zhang, Xing-Xiao;
Journal molecules
Year 2019
DOI
E4596
URL
Keywords
Antimicrobial activity secondary metabolites aspergillus sydowii seawater-derived fungus

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.