Clinical characteristics of Behcet's disease in 453 Egyptian patients suffering from uveitis with gender comparison.

To describe the clinical features in patients with Behcet's disease suffering from uveitis in Egypt and to compare the incidence of findings between both genders.453 subjects fulfilling 1990 Classification criteria for Behcet's disease and having uveitis in at least one eye. Follow-up was done for two years.Oral ulcers and recurrent iridocyclitis occurred to all patients during their disease course. The prevalence of genital ulcers, erythema nodosum, and joint involvement was similar between both sexes. The prevalence of all ocular findings was higher in females except retinal hemorrhages. The incidence of secondary cataract and glaucoma in addition to vitreous opacities were similar between both sexes. 13.7% of patients had GIT manifestations. Vascular complications were present in 128 (28.2%) patients. Aseptic meningitis and hemiplegia were found in males only. 1.7% of males and 3.2% of females suffered from brainstem involvement. Superior sagittal sinus thrombosis was present in females only. Acute phase reactants (ESR & CRP) were significantly higher in females (p<0.0001).Disease characteristics of BD patients with uveitis in Egypt might be different from BD patients from other countries. Markers of inflammation were higher in females compared to males. Ocular manifestations were more common in females.