Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature

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ID: 7921
2019
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Abstract
Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor, with a limited number of published reports. Less than three hundred cases have been reported in the literature and only 18 of these cases have been reported in minor palatal salivary glands, though publication bias is likely a factor. We present a case of a 57-year-old male who was diagnosed with MASC tumor presenting in a minor salivary gland and briefly review the current literature. MASC has a variety of histological features and different range of clinical behaviors. The histopathological diagnosis of MASC can be difficult, and the immunohistochemical profile of MASC is still being updated. The gold standard for MASC diagnosis is cytogenetics, with the majority having a translocation t(12;15)(p133;q25). Presently, there is no conclusive evidence that MASC should be treated differently than any other low-grade malignant salivary gland tumors, though high-grade transformation has been described.
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christian2019mammarycase Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Boliere, Christian;Murphy, James;Qaisi, Mohammed;Manosca, Frances;Fung, Henry;Boliere, Christian;Murphy, James;Qaisi, Mohammed;Manosca, Frances;Fung, Henry;
Journal case reports in dentistry
Year 2019
DOI
10.1155/2019/7416302
URL
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