Plastic Scintillator-Based Microfluidic Devices for Miniaturized Detection of Positron Emission Tomography Radiopharmaceuticals.

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ID: 77916
2018
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Ranked #19 of 117 articles by views in Chemistry (Weinheim an der Bergstrasse, Germany)

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Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [ F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
Reference Key
tarn2018plasticchemistry Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tarn, Mark D;Kızılyer, Nuray Yavuzkanat;Esfahani, Mohammad M N;Joshi, Pankaj;Brown, Nathaniel J;Pamme, Nicole;Jenkins, David G;Archibald, Stephen J;
Journal Chemistry (Weinheim an der Bergstrasse, Germany)
Year 2018
DOI
10.1002/chem.201802395
URL
Keywords
positron emission tomography microfluidics liquid chromatography plastic scintillator radiopharmaceuticals silicon photomultiplier

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