Plastic Scintillator-Based Microfluidic Devices for Miniaturized Detection of Positron Emission Tomography Radiopharmaceuticals.
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2018
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Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [ F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
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tarn2018plasticchemistry
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| Authors | Tarn, Mark D;Kızılyer, Nuray Yavuzkanat;Esfahani, Mohammad M N;Joshi, Pankaj;Brown, Nathaniel J;Pamme, Nicole;Jenkins, David G;Archibald, Stephen J; |
| Journal | Chemistry (Weinheim an der Bergstrasse, Germany) |
| Year | 2018 |
| DOI |
10.1002/chem.201802395
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