Pyrazolo[3,4-d]pyrimidine based scaffold derivatives targeting kinases as anticancer agents

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ID: 77217
2016
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Abstract
Pyrazolopyrimidines are fused heterocyclic ring systems which structurally can consider as bioisosteres of adenine, which is fundamental for every aspect of cell life. Pyrazolo[3,4-d]pyrimidines derivatives have been explored for their inhibitory activity towards various protein kinase enzymes and their role as anticancer agents. The present review to the best of our knowledge is the first compilation on synthesis and medicinal aspects including structure–activity relationships of pyrazolo[3,4-d]pyrimidines reported to date.
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ismail2016pyrazolo34dpyrimidinefuture Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ismail, Nasser S.M.;Ali, Eslam M.H.;Ibrahim, Diaa A.;Serya, Rabah A.T.;Ella, Dalal A. Abou El;
Journal future journal of pharmaceutical sciences
Year 2016
DOI
DOI not found
URL
http://www.sciencedirect.com/science/article/pii/S2314724515300169
Keywords
chemistry Organic Chemistry Pharmacy and materia medica Therapeutics. Pharmacology Medicine Science

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