A multichannel system integrating molecularly imprinted conductive polymers for ultrasensitive voltammetric determination of four steroid hormones in urine.
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ID: 76633
2019
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Abstract
This work reports on a modularized electrochemical method for the determination of the hormones cortisol, progesterone, testosterone and 17β-estradiol in urine. These hormones were employed as templates when generating molecular imprints from aniline and metanilic acid by electropolymerization on the surface of screen-printed electrodes. The electrically conductive imprint was characterized by SEM, AFM and cyclic voltammetry. A four-channel system was then established to enable simultaneous determination of the hormones by cyclic voltammetry. The detection limits for cortisol, progesterone, testosterone and 17β-estradiol are as low as 2, 2.5, 10 and 9 ag·mL (for S/N = 3). Graphical abstract A four-channel system was established to enable simultaneous determination of 4 steroid hormones by cyclic voltammetry and by using moleculalry imprinted polymers.
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lee2019amikrochimica
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| Authors | Lee, Mei-Hwa;Thomas, James L;Liu, Wei-Chiun;Zhang, Zheng-Xiang;Liu, Bin-Da;Yang, Chien-Hsin;Lin, Hung-Yin; |
| Journal | Mikrochimica acta |
| Year | 2019 |
| DOI |
10.1007/s00604-019-3797-7
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