Ozone and oxidation therapies as a solution to the emerging crisis in infectious disease management: a review of current knowledge and experience.

Terapi ozon dan oksidasi sebagai solusi terhadap krisis yang sedang berkembang dalam tata laksana penyakit infeksi: tinjauan pengetahuan dan pengalaman terkini.

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Abstract
Medicine faces crisis with emerging "super bugs," lethal viruses (Ebola), and stealth pathogens such as tick-borne infections. Thousands are dying worldwide of once easily treatable diseases. Ozone therapy, extensively studied, may be a valuable adjunctive or stand-alone therapy. Ebola again ravages Africa with over 2000 already dead, carrying a 65% mortality rate. The world desperately needs safe, inexpensive and effective anti-infective therapy to which microbes will not develop resistance. Oxidation therapies have shown an extremely high safety profile, lacking credible reports of significant injury beyond vein irritation. Ozone therapy, the most studied and least expensive to perform, is in itself a germicide, not an antibiotic, and improves several physiological parameters essential for infection defense. Recent reports indicate very favorable responses to both bacterial and viral disease, inclusive of Ebola. Despite lack of commercial profitability (not patentable), medicine would do well to revisit its pre-antibiotic era oxidation therapy roots, especially ozone in the current crisis.
Dunia kedokteran menghadapi krisis akibat kemunculan "superbug", virus mematikan (Ebola), dan patogen tersembunyi seperti infeksi tular-caplak. Ribuan orang di seluruh dunia meninggal akibat penyakit yang dulunya mudah diobati. Terapi ozon, yang telah diteliti secara ekstensif, dapat menjadi terapi adjuvan atau terapi mandiri yang berharga. Ebola kembali melanda Afrika dengan lebih dari 2.000 kematian yang telah tercatat, membawa tingkat mortalitas sebesar 65%. Dunia sangat membutuhkan terapi anti-infeksi yang aman, murah, dan efektif, yang tidak memicu resistansi mikroba. Terapi oksidasi telah menunjukkan profil keamanan yang sangat tinggi, tanpa adanya laporan kredibel mengenai cedera signifikan selain iritasi vena. Terapi ozon, yang paling banyak diteliti dan paling hemat biaya untuk dilakukan, pada hakikatnya merupakan germisida, bukan antibiotik, serta meningkatkan beberapa parameter fisiologis yang esensial untuk pertahanan terhadap infeksi. Laporan terkini mengindikasikan respons yang sangat baik terhadap penyakit bakteri maupun virus, termasuk Ebola. Terlepas dari minimnya profitabilitas komersial (tidak dapat dipatenkan), dunia kedokteran patut meninjau kembali akar terapi oksidasi dari era pra-antibiotik, khususnya ozon di tengah krisis yang sedang berlangsung saat ini.
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Authors Rowen, Robert Jay;
Journal Medical gas research
Year Year not found
DOI
10.4103/2045-9912.273962
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