Nutritional interventions for autism spectrum disorder.

Clicks: 429
ID: 74541
2019
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Abstract
Autism spectrum disorder (ASD) is an increasingly prevalent neurodevelopmental disorder with considerable clinical heterogeneity. With no cure for the disorder, treatments commonly center around speech and behavioral therapies to improve the characteristic social, behavioral, and communicative symptoms of ASD. Gastrointestinal disturbances are commonly encountered comorbidities that are thought to be not only another symptom of ASD but to also play an active role in modulating the expression of social and behavioral symptoms. Therefore, nutritional interventions are used by a majority of those with ASD both with and without clinical supervision to alleviate gastrointestinal and behavioral symptoms. Despite a considerable interest in dietary interventions, no consensus exists regarding optimal nutritional therapy. Thus, patients and physicians are left to choose from a myriad of dietary protocols. This review, summarizes the state of the current clinical and experimental literature on nutritional interventions for ASD, including gluten-free and casein-free, ketogenic, and specific carbohydrate diets, as well as probiotics, polyunsaturated fatty acids, and dietary supplements (vitamins A, C, B6, and B12; magnesium and folate).
Reference Key
karhu2019nutritionalnutrition Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Karhu, Elisa;Zukerman, Ryan;Eshraghi, Rebecca S;Mittal, Jeenu;Deth, Richard C;Castejon, Ana M;Trivedi, Malav;Mittal, Rahul;Eshraghi, Adrien A;
Journal nutrition reviews
Year 2019
DOI
nuz092
URL
Keywords
dietary supplements probiotics autism spectrum disorder (asd) polyunsaturated fatty acids gluten-free diet casein-free diet ketogenic diet specific carbohydrate diet

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