Ru@CMC/FeO hybrid: an efficient, magnetic, retrievable, self-organized nanocatalyst for green synthesis of pyranopyrazole and polyhydroquinoline derivatives.

Ru incorporated with magnetic nanosized CMC/FeO hybrid (Ru@CMC/FeO) has readily developed by a very simple self-organized procedure of RuCl and Na-CMC/FeO organic/inorganic hybrid. The self-organized fresh and recovered catalyst was well characterized by ICP-AES, FTIR, XRD, TGA-DSC-DTG, SEM-EDS-mapping, TEM, and XPS techniques. The elemental maps confirmed that the Ru species are well dispersed in a homogeneous manner on the surface of CMC/FeO magnetic hybrid nanoparticles. After full characterization, its catalytic activity was investigated in the synthesis of pyranopyrazole and polyhydroquinoline derivatives. Under optimal conditions, all reactions proceeded well and afforded the desired products in excellent yields. There was no significant effect of electron withdrawing or donating nature of substituent on aryl aldehydes in the formation of these target compounds. The salient features of the present new protocol are broad substrate scope, mild reaction conditions, good-to-excellent yields, operational simplicity, energy-efficiency, high atom-economy, easy isolation of products and no column chromatographic separation. Moreover, Ru@CMC/FeO can be easily recovered by using a magnetic field and directly reused for several cycles without significant loss of its activity. The recovered catalyst was confirmed by TEM, XPS, XRD, and SEM-EDS analyses. One-pot multicomponent reactions for green synthesis of pyranopyrazole and polyhydroquinoline derivatives have been performed using a self-organized Ru@CMC/FeO nanocatalyst.