Enhanced photocatalysis and anticancer activity of green hydrothermal synthesized Ag@TiO nanoparticles.

Clicks: 504
ID: 73813
2020
Article Quality & Performance Metrics
Overall Quality Improving Quality
58.9 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment 🥈 High Quality
83.1 /100
Academic Rigor 88.0%
Novelty 78.0%
Clarity 85.0%
Key Strengths
  • Green synthesis approach is highlighted
  • Clear demonstration of photocatalytic and anticancer activity
  • Well-defined experimental parameters
Areas for Improvement
  • Limited information on the long-term stability of the nanoparticles
  • Lack of in vivo studies to support the in vitro anticancer activity
  • Mechanism of ROS generation could be further elucidated
AI Recommendations

The manuscript would benefit from a more detailed discussion on the mechanism of ROS generation and the long-term stability of the nanoparticles. Including in vivo studies would strengthen the anticancer activity claims.

Enhanced v2.0 Analysis NISO/DORA Compliant
NISO/DORA Compliant
High Impact
📊 Established
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2025 Relevance
Relevance
0%
Importance
0%
Authorship
Unknown
Authors
0
Diversity
0%
Research Integrity
COPE Standards
Integrity
0%
Innovation
0%
Interdisciplinary Value
🔀 Cross-disciplinary
70%
Practical Impact Potential
Real-world Applications
75%
Enhanced Evaluation v2.0: Following NISO RP-25-2016, DORA 2025, and COPE assessment standards with 13 quality dimensions.
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Ranked #5 of 150 articles by views in journal of photochemistry and photobiology b, biology

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Abstract
Titanium dioxide (TiO) nanoparticles (NPs) have been doped with varying amounts (0.005, 0.010 and 0.015 M) of silver nanoparticles (Ag NPs) using hydrothermal method. Further, in this work, a green approach was followed for the formation of Ag@TiO NPs using Aloe vera gel as a capping and reducing agent. The structural property confirmed the presence of anatase phase TiO. Increased peak intensity was observed while increasing the Ag concentration. Further, the morphological and optical properties have been studied, which confirmed the effective photocatalytic behavior of the prepared Ag@TiO NPs. The photocatalytic performance of Ag@TiO has been considered for the degradation of picric acid in the visible light region. The concentration at 0.010 M of the prepared Ag@TiO has achieved higher photocatalytic performance within 50 min, which could be attributed to its morphological behavior. Similarly, anticancer activity against lung cancer cell lines (A549) was also determined. The Ag@TiO NPs generated a large quantity of reactive oxygen species (ROS), resulting in complete cancer cell growth suppression after their systemic in vitro administration. Ag@TiO NPs was adsorbed visible light that leads to an enhanced anticancer sensitivity by killing and inhibiting cancer cell reproduction through cell viability assay test. It was clear that 0.015 M of Ag@TiO NPs were highly effective against human lung cancer cell lines and showed increased production of ROS in cancer cell lines due to the medicinal behavior of the Aloe vera gel.
Reference Key
hariharan2020enhancedjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Hariharan, D;Thangamuniyandi, P;Jegatha Christy, A;Vasantharaja, R;Selvakumar, P;Sagadevan, S;Pugazhendhi, A;Nehru, L C;
Journal journal of photochemistry and photobiology b, biology
Year 2020
DOI
S1011-1344(19)30806-1
URL
Keywords
ros photocatalyst hydrothermal synthesis aloe vera cancer cell lines-a549 picric acid

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