Surveillance and impact of occult hepatitis B virus, SEN virus, and Torque teno virus in Egyptian hemodialysis patients with chronic hepatitis C virus infection.

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ID: 73307
2019
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Ranked #7 of 68 articles by views in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

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Abstract
Egypt ranks first regarding the prevalence of HCV infection. Many patients have concomitant diseases like kidney disorders compelling hemodialysis, a procedure carrying the hazard of transmitting other hepatitis viruses. The purpose of this study is to surveil occult hepatitis B virus (HBV), SEN virus (SENV), and torque teno virus (TTV) among chronic HCV patients on maintenance hemodialysis to identify their impacts.A total of325 hemodialysis patients were enrolled and divided into two groups based on HCV RNA testing. Blood samples were collected before hemodialysis. Sera were tested for antibodies to hepatitis B core (HBc) and surface antigens using ELISA. HBV, SENV, and TTV DNAs were detected by PCR. The ALT serum level was measured.HBc antibodies and HBV DNA were detected in 73.1% and 50.8% of group 1 versus 36.4% and 22.6% of group 2. ALT level was higher in group 1 than group 2. SENV was detected in 11.5% of group 1 versus 8.2% of group 2. TTV was detected in 29% of group 1 versus 27% of group 2.There is an increased prevalence of occult HBV in our locality among chronic HCV patients undergoing hemodialysis. The existence of SEN and TT viremia has no clinical impact.
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amer2019surveillanceinternational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Amer, Fatma;Yousif, Monkez M;Mohtady, Heba;Khattab, Rania A;Garagoz, Ergenekon;Ayaz, Khan F M;Hammad, Noha M;
Journal International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Year 2019
DOI
S1201-9712(19)30484-9
URL
Keywords
hemodialysis hepatitis c virus sen virus torque teno virus occult hepatitis b infection

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