Anti-Inflammatory and Immunomodulatory Effects of Barberry () and Its Main Compounds.

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ID: 70878
2019
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Abstract
is a well-known herb in Iran that is widely used as a medicinal plant and a food additive. The aim of this study was to investigate the anti-inflammatory and immunomodulatory effects of Barberry and its main compounds. This narrative review was conducted by searching keywords such as . , Barberry, immunomodulatory, anti-inflammatory, medicinal herbs, plants, and extract, separately or combined in various databases, such as Web of Sciences, PubMed, and Scopus. According to the inclusion and exclusion criteria, just English language articles, which reported effective whole plants or herbal compounds, were included. 21 articles were reviewed in this study. In the models (mice, rats, and human cells) and in the models (some organ cells such as the spleen, kidney, blood, and brain), . and its main components showed anti-inflammatory effects in both models. The main mechanisms were the shift of cell immune response to Th2, T reg induction, inhibition of inflammatory cytokines (IL-1, TNF, and IFN-), and stimulation of IL-4 and IL-10. The induction of apoptosis in APCs and other effector cells was another important mechanism.
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kalmarzi2019antiinflammatoryoxidative Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kalmarzi, Rasool Nasiri;Naleini, Seyyed Nima;Ashtary-Larky, Damoon;Peluso, Ilaria;Jouybari, Leila;Rafi, Alireza;Ghorat, Fereshteh;Heidari, Nishteman;Sharifian, Faezeh;Mardaneh, Jalal;Aiello, Paola;Helbi, Sobhan;Kooti, Wesam;
Journal oxidative medicine and cellular longevity
Year 2019
DOI
10.1155/2019/6183965
URL
Keywords
additives microplastics food chain nanoplastics potential toxicity

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