Study of angiotensin converting enzyme (ACE) activity in patients with atherosclerosis and in healthy individuals.
Clicks: 469
ID: 68534
2018
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
68.4
/100
469 views
344 readers
Trending
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #2 of 3 articles by views in yafteh
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Background: Coronary artery disease (CAD) is currently the leading cause of death among people around the world. The main cause of CAD is atherosclerosis or vascular arrest. In the etiology of this disease, various factors, including genetic factors, are involved. In this study, the effect of angiotensin converting enzyme (ACE) as a risk factor was evaluated. Increasing ACE activity by enhancing the synthesis of angiotensin II is likely to contribute to the risk of atherosclerosis.
Materials and Methods: In this case-control study, 145 healthy individuals and 154 patients were selected from among patients referred to the Shahid Madani Hospital. Absorption of atherosclerosis in healthy individuals and atherosclerosis in patients with standardized angiography was confirmed. The case and control groups were matched for age and gender. A 5 ml sample of blood was taken from each person, and the serum was isolated. ACE activity was measured using HHL substrate and HPLC techniques.
Results: The results showed that the level of ACE activity in patients with atherosclerosis was higher than those in the control group and this increase was statistically significant (P<0.05).
Conclusion: According to the results, increased ACE activity can be an independent factor in the incidence of CAD and can be used to assess the risk of disease.
| Reference Key |
shahsavari2018studyyafteh
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Shahsavari, GHolamreza ;Nouryazdan, Negar;Heidary, Rohollah;Birjandi, Mehdi; |
| Journal | yafteh |
| Year | 2018 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.