Biomarkers for the prediction of acute ongoing arterial plaque rupture

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ID: 6817
2013
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Ranked #198 of 242 articles by views in research reports in clinical cardiology

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Abstract
Biomarkers for the prediction of acute ongoing arterial plaque rupture Yuan-Lin Guo, Jian-Jun Li Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China Abstract: Acute coronary syndrome (ACS) is the main cause of mortality for coronary artery disease (CAD). Accordingly, earlier detection and diagnosis might be a key point for reducing the mortality in patients with ACS. One promising strategy is biomarker measurement in patients with ACS. Biomarkers are generally considered to be plasma measurements of molecules, proteins, or enzymes that provide independent diagnostic and prognostic values that can reflect underlying disease state and condition, especially repeated measurements. Nowadays, the most widely used biomarkers to identify or predict ACS are high sensitivity C-reactive protein (hs-CRP) and high sensitivity troponin T/I (hs-TnT/I). The aim of the present review was principally to summarize recent evidence regarding some new biomarkers by which we could directly predict acute ongoing arterial plaque rupture, which may help to identify at-risk patients earlier than hs-CRP or hs-TnT/I. Keywords: matrix metalloproteinase-9, lipoprotein associated phospholipase A2, myeloperoxidase, soluble lectin-like oxidized low-density lipoprotein receptor-1, pregnancy-associated plasma protein A, placental growth factor, acute coronary syndrome
Reference Key
yuanlin2013biomarkersresearch Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yuan-Lin Guo;Jian-Jun Li and
Journal research reports in clinical cardiology
Year 2013
DOI
10.2147/RRCC.S32129
URL
Keywords Keywords not found

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