High resolution non-invasive intraocular pressure monitoring by use of graphene woven fabrics on contact lens.

Monitoring intracorporal pressures are important for health care and diagnosis. In this work, a contact lens tonometer employing graphene woven fabrics (GWFs), which indicate great sensibility of resistance to strain, flexibility, stretchability, transparency, and biocompatibility, is proposed for real-time monitoring intraocular pressure (IOP) with high resolution. The mechanical properties of the device during the deformation were analyzed, and the sensitivity of the fabricated device was tested on a mimic human eyeball. In vitro experiments on porcine eyes were executed to test the effectiveness of the device. The change rate of resistance under different IOP was tested. Also, the relationship between the current changes and IOP variation when keeping the voltage constant for different devices was obtained. The contact lens tonometers with GWFs as high-resolution sensing element have shown a promising prospective to realize the low-cost disposable sensing contact lens with lower power.