Genome evolution in the allotetraploid frog Xenopus laevis.

Clicks: 384
ID: 66127
2016
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #39 of 375 articles by views in Nature

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 375 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
To explore the origins and consequences of tetraploidy in the African clawed frog, we sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis genome. We characterize the allotetraploid origin of X. laevis by partitioning its genome into two homoeologous subgenomes, marked by distinct families of 'fossil' transposable elements. On the basis of the activity of these elements and the age of hundreds of unitary pseudogenes, we estimate that the two diploid progenitor species diverged around 34 million years ago (Ma) and combined to form an allotetraploid around 17-18 Ma. More than 56% of all genes were retained in two homoeologous copies. Protein function, gene expression, and the amount of conserved flanking sequence all correlate with retention rates. The subgenomes have evolved asymmetrically, with one chromosome set more often preserving the ancestral state and the other experiencing more gene loss, deletion, rearrangement, and reduced gene expression.
Reference Key
session2016genomenature Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Session, Adam M;Uno, Yoshinobu;Kwon, Taejoon;Chapman, Jarrod A;Toyoda, Atsushi;Takahashi, Shuji;Fukui, Akimasa;Hikosaka, Akira;Suzuki, Atsushi;Kondo, Mariko;van Heeringen, Simon J;Quigley, Ian;Heinz, Sven;Ogino, Hajime;Ochi, Haruki;Hellsten, Uffe;Lyons, Jessica B;Simakov, Oleg;Putnam, Nicholas;Stites, Jonathan;Kuroki, Yoko;Tanaka, Toshiaki;Michiue, Tatsuo;Watanabe, Minoru;Bogdanovic, Ozren;Lister, Ryan;Georgiou, Georgios;Paranjpe, Sarita S;van Kruijsbergen, Ila;Shu, Shengquiang;Carlson, Joseph;Kinoshita, Tsutomu;Ohta, Yuko;Mawaribuchi, Shuuji;Jenkins, Jerry;Grimwood, Jane;Schmutz, Jeremy;Mitros, Therese;Mozaffari, Sahar V;Suzuki, Yutaka;Haramoto, Yoshikazu;Yamamoto, Takamasa S;Takagi, Chiyo;Heald, Rebecca;Miller, Kelly;Haudenschild, Christian;Kitzman, Jacob;Nakayama, Takuya;Izutsu, Yumi;Robert, Jacques;Fortriede, Joshua;Burns, Kevin;Lotay, Vaneet;Karimi, Kamran;Yasuoka, Yuuri;Dichmann, Darwin S;Flajnik, Martin F;Houston, Douglas W;Shendure, Jay;DuPasquier, Louis;Vize, Peter D;Zorn, Aaron M;Ito, Michihiko;Marcotte, Edward M;Wallingford, John B;Ito, Yuzuru;Asashima, Makoto;Ueno, Naoto;Matsuda, Yoichi;Veenstra, Gert Jan C;Fujiyama, Asao;Harland, Richard M;Taira, Masanori;Rokhsar, Daniel S;
Journal Nature
Year 2016
DOI
10.1038/nature19840
URL
Keywords
aggression narcissism five-factor model five factor narcissism inventory dominance analysis

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.