Trichothecenes in Cereal Grains - An Update.

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ID: 65572
2019
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Abstract
Trichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the genus that infect cereal grain crops. Different trichothecene-producing species and strains have different trichothecene chemotypes belonging to the Type A and B class. These fungi cause a disease of small grain cereals, called Fusarium head blight, and their toxins contaminate host tissues. As potent inhibitors of eukaryotic protein synthesis, trichothecenes pose a health risk to human and animal consumers of infected cereal grains. In 2009, Foroud and Eudes published a review of trichothecenes in cereal grains for human consumption. As an update to this review, the work herein provides a comprehensive and multi-disciplinary review of the trichothecenes covering topics in chemistry and biochemistry, pathogen biology, trichothecene toxicity, molecular mechanisms of resistance or detoxification, genetics of resistance and breeding strategies to reduce their contamination of wheat and barley.
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foroud2019trichothecenestoxins Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Foroud, Nora A;Baines, Danica;Gagkaeva, Tatiana Y;Thakor, Nehal;Badea, Ana;Steiner, Barbara;Bürstmayr, Maria;Bürstmayr, Hermann;
Journal Toxins
Year 2019
DOI
E634
URL
Keywords
resistance wheat deoxynivalenol barley t-2 toxin fusarium fusarium head blight (fhb)

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