Vitamin A and zinc deficiencies among tuberculosis patients in Ethiopia.

Clicks: 360
ID: 65473
2018
Article Quality & Performance Metrics
Overall Quality Improving Quality
0.0 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment
Not analyzed
Abstract
The link between tuberculosis (TB) and malnutrition has long been recognized. Vitamin A and zinc deficiencies may reduce the host defenses and increase the risk for diseases.The aim of the present study was to estimate the difference in vitamin A and zinc deficiencies together with dietary intakes among pulmonary TB patients and controls.A case-control study design was employed to undertake this study in North Shewa, Ethiopia. Sputum smear examination, high-performance liquid chromatography (HPLC), flame atomic absorption spectrometry (FAAS), and enzyme-linked immunosorbent assay (ELISA) were used to analyse acid fast bacilli (AFB), vitamin A, zinc, and C-reactive protein (CRP), respectively. Dietary intake was assessed using a 24-h recall questionnaire. Mann-Whitney U test, Kruskal-Wallis test, Chi-square, odds ratio (OR), Spearman correlation, and multinomial logistic regression model were computed for data analyses.In this study, 62 TB cases and 59 controls were included. The proportions of vitamin A deficiency among TB cases and controls were 56.4% and 39.0%, respectively. All TB cases and 92.5% controls were zinc deficient. The odds of TB cases with deficiencies of vitamin A and zinc was 2.3 (95% CI: 1.1 to 4.8)times more likely as compared to the controls. More than 80% of all participants had below average fulfilment of energy and vitamin A intakes.Vitamin A and zinc deficiencies are severe problems among TB patients. Moreover, undernutrition determines the development of TB. Therefore, the management programs of TB need to address the problems of vitamin A and zinc deficiencies together with protein-energy malnutrition.
Reference Key
keflie2018vitaminjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Keflie, Tibebeselassie Seyoum;Samuel, Aregash;Woldegiorgis, Ashagrie Zewdu;Mihret, Adane;Abebe, Markos;Biesalski, Hans Konrad;
Journal journal of clinical tuberculosis and other mycobacterial diseases
Year 2018
DOI
10.1016/j.jctube.2018.05.002
URL
Keywords
Zinc ethiopia tuberculosis vitamin a ci, confidence interval sd, standard deviation hplc, high performance liquid chromatography afb, acid fast bacilli bmi, body mass index crp, c-reactive protein dds, dietary diversity score elisa, enzyme-linked immunosorbent assay faas, flame atomic absorption spectrometry iqr, inter quartile range izincg, international zinc nutrition consultative group muac, mid upper arm circumference tb, tuberculosis vif, variance inflation factor

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.