Asymptomatic malaria in the clinical and public health context.

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ID: 65327
2019
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Abstract
: Historically, the global community has focused on the control of symptomatic malaria. However, interest in asymptomatic malaria has been growing, particularly in the context of malaria elimination.: We undertook a comprehensive PubMed literature review on asymptomatic malaria as it relates to detection and elimination with emphasis between 2014-2019. Diagnostic tools with a low limit of detection (LOD) have allowed us to develop a more detailed understanding of asymptomatic malaria and its impact. These highly sensitive diagnostics has demonstrated that the prevalence of asymptomatic malaria is greater than previously thought. In addition, it is now possible to detect the malaria reservoir in the community, something that was previously not feasible. Asymptomatic malaria has previously not been treated, but research has begun to examine whether treating individuals with asymptomatic malaria may lead to health benefits. Finally, we have begun to understand the importance of asymptomatic malaria in ongoing transmission.: Therefore, with malaria elimination back on the agenda, asymptomatic malaria can no longer be ignored, especially in light of new ultra-sensitive diagnostic tools, and a new global strategy is required.
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cheaveau2019asymptomaticexpert Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Cheaveau, James;Mogollon, Daniel Castaneda;Mohon, Md Abu Naser;Golassa, Lemu;Yewhalaw, Delenasaw;Pillai, Dylan R;
Journal expert review of anti-infective therapy
Year 2019
DOI
10.1080/14787210.2019.1693259
URL
Keywords
malaria diagnosis antimalarial reservoir elimination asymptomatic clinical disease

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