CHANGES IN BLOOD COUNT AND LYMPHOCYTE MICRONUCLEI IN PIGLETS AFTER WHOLE-BODY IRRADIATION.
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2019
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Abstract
Biodosimetry is focused on effects of ionizing radiation at cellular and molecular levels of living organisms so that a qualified retrospective estimate of radiation load can be made. Two biodosimetry methods were evaluated in irradiated piglets: complete blood count analysis and quantification of chromosomal aberrations in lymphocytes using a micronucleus test. Animals were whole-body irradiated with gamma radiation at doses of 0-10 Gy. The analysis of complete blood count was performed at intervals ranging from 0 to 48 hours. Micronuclei were measured at 4 hours after irradiation. Changes in lymphocyte counts and increased levels of micronuclei reflected received dose of ionizing radiation.
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jeliov2019changesradiation
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| Authors | Jeličová, Marcela;Lierová, Anna;Šinkorová, Zuzana;Pejchal, Jaroslav; |
| Journal | Radiation protection dosimetry |
| Year | 2019 |
| DOI |
ncz198
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