CHANGES IN BLOOD COUNT AND LYMPHOCYTE MICRONUCLEI IN PIGLETS AFTER WHOLE-BODY IRRADIATION.

Clicks: 307
ID: 65014
2019
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Abstract
Biodosimetry is focused on effects of ionizing radiation at cellular and molecular levels of living organisms so that a qualified retrospective estimate of radiation load can be made. Two biodosimetry methods were evaluated in irradiated piglets: complete blood count analysis and quantification of chromosomal aberrations in lymphocytes using a micronucleus test. Animals were whole-body irradiated with gamma radiation at doses of 0-10 Gy. The analysis of complete blood count was performed at intervals ranging from 0 to 48 hours. Micronuclei were measured at 4 hours after irradiation. Changes in lymphocyte counts and increased levels of micronuclei reflected received dose of ionizing radiation.
Reference Key
jeliov2019changesradiation Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jeličová, Marcela;Lierová, Anna;Šinkorová, Zuzana;Pejchal, Jaroslav;
Journal Radiation protection dosimetry
Year 2019
DOI
ncz198
URL
Keywords
carbamate pesticides dispersive solid-phase extraction multi-plug filtration cleanup ultra-performance liquid chromatography/tandem mass spectrometry

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