Copper-catalyzed acylation of pyrazolones with aldehydes to afford 4-acylpyrazolones.

Clicks: 299
ID: 64665
2019
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Abstract
Copper-catalyzed direct acylation of the alkenyl C-H bond in 1,2-dihydro-3H-pyrazol-3-ones has been developed, affording a series of 4-acylpyrazolones in moderate to good yields. Notably, this protocol involves readily accessible substrates and reagents, which have good functional group tolerance leading to pyrazolone derivatives under mild reaction conditions.
Reference Key
xiao2019coppercatalyzedorganic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Xiao, Yan;Wu, Xiaopeng;Teng, Jiangang;Sun, Song;Yu, Jin-Tao;Cheng, Jiang;
Journal Organic & biomolecular chemistry
Year 2019
DOI
10.1039/c9ob01486a
URL
Keywords
uplc-ms/ms monosaccharide composition polyporus umbellatus polysaccharide pre-column derivation

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