Biolubrication synergy: Hyaluronan - Phospholipid interactions at interfaces.

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ID: 64604
2019
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Ranked #5 of 20 articles by views in advances in colloid and interface science

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Abstract
The manner in which nature has solved lubrication issues has fascinated scientists for centuries, in particular when considering that lubrication is achieved in aqueous media. The most outstanding system in this respect is likely the synovial joint, where close to frictionless motion is realized under different loads and shear rates. This review article focuses on two components present in the synovial area, hyaluronan and phospholipids. We recapitulate what has been learned about their interactions at interfaces from recent experiments, with focus on results obtained using reflectivity techniques at large scale facilities. In parallel, modelling experiments have been carried out and from these efforts new detailed knowledge about how hyaluronan and phospholipids interact has been gained. In this review we combine findings from modelling and experiments to gain deeper insight. Finally, we summarize what has been learned of the lubrication performance of mixtures of phospholipids and hyaluronan.
Reference Key
ddinait2019biolubricationadvances Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Dėdinaitė, Andra;Wieland, D C Florian;Bełdowski, Piotr;Claesson, Per M;
Journal advances in colloid and interface science
Year 2019
DOI
S0001-8686(19)30326-4
URL
Keywords
association hyaluronan interface structure lubrication synergy phospholipid

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