Association of seminal angiotensinogen with sperm motility and morphology in male infertility.

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ID: 63004
2019
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Abstract
Many researchers have shown that renin-angiotensin system (RAS) is involved in various important aspects of male reproduction. In this study, we assessed whether abnormal levels of seminal angiotensinogen (AGT) may be associated with semen parameters in infertile males. A total of 115 male patients were recruited, and semen parameters, seminal AGT and the electrolytes including K , Na , Cl , P and Ca were evaluated. According to the World Health Organization (WHO) 2010 criteria, the patients were divided into two groups: G1 group with normal semen parameters (n = 42) and G2 group with subnormal semen parameters (n = 73). The level of seminal AGT was significantly higher in G2 group compared with G1 group. Moreover, the level of AGT was negatively correlated with the percentage of total motility (r = -.322, p = .000), progressive motility (PR) (r = -.339, p = .000) and morphologically normal forms (r = -.263, p = .004). This study suggests that elevated seminal AGT level is associated with increased risk of asthenospermia and teratozoospermia.
Reference Key
zhu2019associationandrologia Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhu, Xi;Xie, Tingting;Zhan, Xiaomin;Liu, Li;Yang, Xiaoping;Xu, Xiya;Ye, Wenting;Song, Yali;
Journal Andrologia
Year 2019
DOI
10.1111/and.13421
URL
Keywords
male infertility angiotensinogen sperm malformation sperm motility

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