[8+3]-Cycloaddition of Tropones with Azaoxyallyl Cations.

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2019
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Abstract
Although azaoxyallyl cations are widely used as 1,3-dipoles for various cycloaddition reactions leading to nitrogen-containing heterocycles, their application in higher-order cycloaddition reaction remains scarce. Herein, we present the [8+3]-cycloaddition reaction of tropones with in situ generated azaoxyallyl cations allowing the one-step construction of cycloheptatriene-fused 1,4-oxazinones in moderate to good yields. This base-promoted new carbon-oxygen and carbon-nitrogen bond-forming reaction takes place under mild conditions in the absence of transition metal catalysts.
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Authors Roy, Tony;Jacob, Anu;Bhattacharjee, Subrata;Biju, Akkattu T;
Journal Chemistry, an Asian journal
Year 2019
DOI
10.1002/asia.201901198
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