The Role of TRAIL/DRs in the Modulation of Immune Cells and Responses.

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2019
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Abstract
Expression of TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) by immune cells can lead to the induction of apoptosis in tumor cells. However, it becomes increasingly clear that the interaction of TRAIL and its death receptors (DRs) can also directly impact immune cells and influence immune responses. Here, we review what is known about the role of TRAIL/DRs in immune cells and immune responses in general and in the tumor microenvironment in particular.
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sag2019thecancers Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sag, Duygu;Ayyildiz, Zeynep Ozge;Gunalp, Sinem;Wingender, Gerhard;
Journal Cancers
Year 2019
DOI
E1469
URL
Keywords
apoptosis tumor immune regulation lymphoid cells myeloid cells

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