Feasibility of predicting live birth by combining conventional embryo evaluation with artificial intelligence applied to a blastocyst image in patients classified by age.

Factibilidad de predecir el nacimiento vivo combinando la evaluación embrionaria convencional con inteligencia artificial aplicada a una imagen de blastocisto en pacientes clasificadas por edad.

Clicks: 442
ID: 60932
2019
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Star

Ranked #1 of 2 articles by views in reproductive medicine and biology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Abstract
To identify the multivariate logistic regression in a combination (combination method) involving artificial intelligence (AI) classifiers in images of blastocysts along with a conventional embryo evaluation (CEE) to predict the probability of accomplishing a live birth in patients classified by maternal age.Retrospectively, a total of 5691 blastocysts were enrolled. Images captured 115 hours or 139 hours if not yet sufficiently large after insemination were classified according to age as follows: <35, 35-37, 38-39, 40-41, and ≥42 years old. The classifiers for each category were created by using convolutional neural networks associated with deep learning. Next, the feasibility of a method combining AI with multivariate logistic model functions by CEE was investigated.The values of the area under the curve (AUC) and the accuracies to predict live birth achieved by the CEE/AI/combination methods were 0.651/0.634/0.655, 0.697/0.688/0.723, 0.771/0.728/0.791, 0.788/0.743/0.806 and 0.820/0.837/0.888, and 0.631/0.647/0.616, 0.687/0.675/0.671, 0.725/0.697/0.732, 0.714/0.776/0.801, and 0.910/0.866/0.784 for age categories of <35, 35-37, 38-39, 40-41, and ≥42 years old, respectively.Though there were mostly no significant differences regarding the AUC and the sensitivity plus specificity in all age categories, the combination method seemed to be the best.
Identificar la regresión logística multivariada en una combinación (método combinado) que integra clasificadores de inteligencia artificial (IA) en imágenes de blastocistos junto con una evaluación embrionaria convencional (EEC) para predecir la probabilidad de lograr un nacido vivo en pacientes clasificadas por edad materna. Retrospectivamente, se incluyó un total de 5691 blastocistos. Las imágenes capturadas a las 115 horas o a las 139 horas posteriores a la inseminación (si aún no tenían un tamaño suficiente) se clasificaron según la edad de la siguiente manera: <35, 35-37, 38-39, 40-41 y ≥42 años. Los clasificadores para cada categoría se generaron mediante el uso de redes neuronales convolucionales asociadas con aprendizaje profundo. A continuación, se investigó la viabilidad de un método que combina la IA con funciones de modelos logísticos multivariados mediante la EEC. Los valores del área bajo la curva (AUC) y las exactitudes para predecir el nacido vivo alcanzados por los métodos de EEC/IA/combinación fueron de 0.651/0.634/0.655, 0.697/0.688/0.723, 0.771/0.728/0.791, 0.788/0.743/0.806 y 0.820/0.837/0.888, y de 0.631/0.647/0.616, 0.687/0.675/0.671, 0.725/0.697/0.732, 0.714/0.776/0.801 y 0.910/0.866/0.784 para las categorías de edad de <35, 35-37, 38-39, 40-41 y ≥42 años, respectivamente. Aunque en su mayoría no hubo diferencias significativas con respecto al AUC y a la sensibilidad más especificidad en todas las categorías de edad, el método combinado pareció ser el mejor.
Reference Key
miyagi2019feasibilityreproductive Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Miyagi, Yasunari;Habara, Toshihiro;Hirata, Rei;Hayashi, Nobuyoshi;
Journal reproductive medicine and biology
Year 2019
DOI
10.1002/rmb2.12284
URL
Keywords

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

No comments yet. Be the first to comment on this article.