Synthesis, Characterization and Antimicrobial Activity of Garcinol Capped Silver Nanoparticles.

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ID: 60637
2019
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Abstract
Garcinol, a well-known medicinal phytochemical, was extracted and isolated from the dried fruit rinds of . In this study, garcinol has successfully used to reduce silver ions to silver in order to synthesize G-AgNPs. The formation and the structure of G-AgNPs were confirmed by UV-Visible spectroscopy, FTIR spectroscopy and TEM. The antimicrobial activity of garcinol and G-AgNPs were investigated by well diffusion assay, broth micro dilution assay and time-kill kinetic study, over selected five microbial species including (ATCC 25623), (ATCC 27853), (ATCC 25922), (ATCC 10231) and clinical isolates of Methicillin (MRSA). Antimicrobial activity of G-AgNPs was compared with the chemically synthesized silver nanoparticles (AgNPs). The formation of G-AgNPs is a promising novel approach to enhance the biologically activeness of silver nanoparticle and to increase the water solubility of garcinol which provides a significant array of therapeutic applications.
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fernando2019synthesisjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors H N Fernando, K Gur Kumarasinghe, T Dcp Gunasekara, H Psk Wijekoon, E Mak Ekanayaka, S P Rajapaksha, S Sn Fernando, P M Jayaweera
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Journal Journal of microbiology and biotechnology
Year 2019
DOI
10.4014/jmb.1904.04032
URL
Keywords
Antimicrobial activity Silver nanoparticles garcinol garcinol capped silver nanoparticles time-kill kinetic studies

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