CHROMOSOMAL ABNORMALITIES IN PATIENTS WITH RECURRENT MISCARRIAGE

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ID: 59712
2012
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Abstract
Chromosomal abnormalities are involved in the etiology of recurrent spontaneous pregnancy loss and sub-fertility. The purpose of this study was to determine the frequency and contribution of chromosomal abnormalities in recurrent miscarriages. The results obtained and literature review are helpful in understanding the importance of cytogenetics analysis of female infertility. To investigate the distribution of chromosomal abnormalities in the Romanian population with recurrent miscarriage, karyotype analysis by G-banding was performed from peripheral blood in 967 women infertility. Results: Chromosomal abnormalities were found to 79 women (8,17%). The percentage of chromosomal abnormalities in the studied population correlates with the data in the literature. Chromosomal abnormalities could play the important role in etiology of infertility and are more frequently detected in this group of patients compared to general population. In the infertile couples balanced chromosomal abnormalities are the main cause of spontaneous abortions.
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mierla2012chromosomalanalele Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Mierla, Daniela;Radoi, Viorica;Stoian, Veronica;
Journal analele Ştiinţifice ale universităţii alexandru ioan cuza din iași,sectiunea ii a : genetica si biologie moleculara
Year 2012
DOI
DOI not found
URL
http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/962
Keywords
Therapeutics. Pharmacology Medicine (General) Medicine public aspects of medicine gynecology and obstetrics genetics internal medicine reproduction

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