A single mega dose of vitamin D3 improves selected physical variables in vitamin D insufficient young amateur soccer players: a randomized controlled trial.

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2019
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Abstract
This randomized controlled trial aimed to test whether vitamin D (VD) supplementation affects measures of physical performance in VD-insufficient mildly trained children. Thirty-six recreationally soccer player boys were randomly assigned to single dose (200,000 IU) of VD3 (n=19) or placebo (n=17). Plasma 25-hydroxyvitamin D (25-OHD) was assessed and measures of physical performance (i.e. vertical and standing broad jumps, triple hop, 10-m and 30-m sprints, shuttle run) were performed before and 12 weeks after the loading dose. Mixed ANCOVA models were performed and effect size was estimated by partial eta squared (ηp2). Baseline 25-OHD and physical variables were equivalent in the two groups. Twelve weeks after VD loading, plasma 25-OHD increased and physical variables improved in VD group, only. There was a significant interaction effects for group by time for vertical jump (F=14.9, p=0.001, ηp2=0.394), triple hop jump (F=24.2, p<0.001, ηp2=0.513), 10-m (F=4.46, p=0.046, ηp2=0.162) and 30-m (F=6.56, p=0.017, ηp2=0.222) sprints, and shuttle run (F=13.4, p=0.001, ηp2=0.369). In conclusion, a single bolus of VD3 resulted in significant improvements in jumping ability, agility, and running speed in VD-insufficient mildly trained children. The findings suggest that correcting VD deficit might be beneficial for physical performance. • A mega dose of vitamin D3 improves jumping ability, agility, and running speed in VD-insufficient mildly trained children • Effect of vitamin D on measures of physical performance is noticeable three months after the loading dose.
Reference Key
bezrati2019aapplied Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Bezrati, Ikram;Ben Fradj, Mohamed Kacem;Hammami, Raouf;Ouerghi, Nejmeddine;Padulo, Johnny;Feki, Moncef;
Journal applied physiology, nutrition, and metabolism = physiologie appliquee, nutrition et metabolisme
Year 2019
DOI
10.1139/apnm-2019-0525
URL
Keywords
Breast cancer epigenetics transcriptional silencing erbb2/her2 prc2 polycomb repressor complex 2 trastuzumab resistance endogenous retroviruses immune surveillance type i interferon signaling

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