Arylation of Click Triazoles with Diaryliodonium Salts.

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ID: 58119
2019
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Abstract
A robust, selective and highly efficient method for the preparation of 1,3,4-triaryl 1,2,3-triazolium salts has been developed. It features arylation of a click triazole with a diaryliodonium salt in the presence of a copper catalyst under neat conditions. The presence of pyridine functionality is tolerated, enabling the first access to key precursors of pyridyl-mesoionic carbene ligands. The method has been integrated into a one-pot protocol with a terminal alkyne, sodium azide, and diaryliodonium salt as staring compounds.
Reference Key
virant2019arylationthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Virant, Miha;Košmrlj, Janez;
Journal The Journal of organic chemistry
Year 2019
DOI
10.1021/acs.joc.9b02197
URL
Keywords
antioxidant 1,2,3-Triazole antitumor vitamin c hif-1 quantum-chemical modelling

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