Disseminated Autochthonous Dermal Leishmaniasis Caused by (PCM2 Trang) in a Patient from Central Thailand Infected with Human Immunodeficiency Virus.

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ID: 58017
2017
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Ranked #17 of 64 articles by views in The American journal of tropical medicine and hygiene

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Abstract
AbstractSeveral case reports of autochthonous leishmaniasis in Thailand have been published since 1996. Most of the previous cases presented with visceral leishmaniasis (VL) and were mostly reported in southern part of Thailand. Recently, it has been evident that is the main cause of infection in Thailand. However, (PCM2 Trang isolate) was found to be of a separate lineage with restricted distribution in southern Thailand and also a cause of disseminated dermal and visceral leishmaniasis in one published case. Here we report the first patient from central Thailand with human immunodeficiency virus infection presenting with disseminated dermal leishmaniasis. Polymerase chain reaction and DNA sequencing analysis (large subunit of RNA polymerase II and 18S ribosomal RNA internal transcribed spacer 1) from the tissue biopsy sample revealed the pathogen sequences to be highly homologous to PCM2 Trang strain previously reported from southern Thailand.
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supsrisunjai2017disseminatedthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Supsrisunjai, Chavalit;Kootiratrakarn, Tanawatt;Puangpet, Pailin;Bunnag, Thareena;Chaowalit, Prapaipit;Wessagowit, Vesarat;
Journal The American journal of tropical medicine and hygiene
Year 2017
DOI
10.4269/ajtmh.16-0472
URL
Keywords
induction chemotherapy isavuconazole posaconazole carbapenemase fluoroquinolone prophylaxis t2 magnetic resonance

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