Synthesis of bi- and bis-1,2,3-triazoles by copper-catalyzed Huisgen cycloaddition: A family of valuable products by click chemistry.

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ID: 57906
2015
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Abstract
The Cu(I)-catalyzed azide-alkyne cycloaddition reaction, also known as click chemistry, has become a useful tool for the facile formation of 1,2,3-triazoles. Specifically, the utility of this reaction has been demonstrated by the synthesis of structurally diverse bi- and bis-1,2,3-triazoles. The present review focuses on the synthesis of such bi- and bistriazoles and the importance of using copper-promoted click chemistry (CuAAC) for such transformations. In addition, the application of bitriazoles and the related CuAAAC reaction in different fields, including medicinal chemistry, coordination chemistry, biochemistry, and supramolecular chemistry, have been highlighted.
Reference Key
zheng2015synthesisbeilstein Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zheng, Zhan-Jiang;Wang, Ding;Xu, Zheng;Xu, Li-Wen;
Journal Beilstein journal of organic chemistry
Year 2015
DOI
10.3762/bjoc.11.276
URL
https://doi.org/10.3762/bjoc.11.276
Keywords
Click chemistry homogeneous catalysis bistriazoles cycloaddition oxidative coupling

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