Oocyte donation in donors with levonorgestrel intrauterine device: a good match?

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ID: 57088
2019
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Abstract
Does the levonorgestrel-releasing intrauterine device (LNG-IUD) influence cumulative live birth rate (CLBR) in oocyte donor cycles?Retrospective cohort study based on prospectively collected data from 1 May 2009 to 31 December 2017, without attrition, consisting of 491 consecutive cycles of vitrified oocyte donation, none lost to follow-up (unique donor-recipient pairs). All donors underwent ovarian stimulation using gonadotrophin releasing hormone (GnRH) antagonist co-treatment and GnRH agonist trigger. CLBR was chosen as primary outcome measure.In total, 103 (21.0%) cycles were carried out in donors carrying a LNG-IUD. In 388 (79.0%) cycles, no LNG-IUD was present. After confounder-adjustment, the use of an LNG-IUD did not have a statistically significant influence on CLBR.The LNG-IUD does not negatively affect CLBR.
Reference Key
galvo2019oocytereproductive Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Galvão, Ana;Karakus, Gunes;Racca, Annalisa;Santos-Ribeiro, Samuel;De Munck, Neelke;Drakopoulos, Panagiotis;De Vos, Michel;Verheyen, Greta;Tournaye, Herman;Blockeel, Christophe;
Journal reproductive biomedicine online
Year 2019
DOI
S1472-6483(19)30586-3
URL
Keywords
ivf oocytes bologna criteria modified natural cycle poor responders

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