Severe Cardiorespiratory and Neurologic Symptoms in a Neonate due to Mepivacaine Intoxication

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ID: 55672
2019
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Abstract
Local anesthesia with mepivacaine is used for vaginal deliveries and for minor surgeries of the vagina and perineum as repair of an episiotomy or perineal laceration. Neonatal intoxication caused by local anesthesia with mepivacaine for maternal episiotomy has been rarely reported. We present a case of a term female infant with unexplained cardiorespiratory distress and several neurologic findings, including seizures, one hour after birth. Electrocardiogram showed a second-degree atrioventricular block and a left-bundle branch block. Blood measures in the patient revealed a high mepivacaine level following local anesthesia for maternal episiotomy. Because of the increasing practice of local anesthesia, high awareness for neonatal intoxication and further research in safe elimination therapy in neonates is needed.
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mooren2019severecase Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Mooren, Maurike de Groot-van der;Quint, Sabine;Knobbe, Ingmar;Cronie, Doug;Weissenbruch, Mirjam van;
Journal case reports in pediatrics
Year 2019
DOI
DOI not found
URL
http://dx.doi.org/10.1155/2019/4013564
Keywords
Medicine (General) Pediatrics surgery Diseases of the circulatory (Cardiovascular) system Medical emergencies. Critical care. Intensive care. First aid

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